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Pilocytic astrocytoma
7 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
Otodental syndrome
1 OMIM reference -
1 associated gene
25 signs/symptoms
Pilocytic astrocytoma
Otodental syndrome

BRAF
(UniProt - OMIM)
 FGF3
(UniProt - OMIM)
FGFR1
(UniProt - OMIM)
KIAA1549
(UniProt - OMIM)
KRAS
(UniProt - OMIM)
NTRK2
(UniProt - OMIM)
RAF1
(UniProt - OMIM)
SRGAP3
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
FGFR1
(0.52)
FGF3


Citations in the biomedical literature:


Pilocytic astrocytoma
BRAF FGFR1 KIAA1549 KRAS NTRK2 RAF1
SRGAP3
Otodental syndrome
FGF3



Pilocytic astrocytoma
Otodental syndrome

Synonym(s):
(no synonyms)

Synonym(s):
- Globodontia
- Otodental dysplasia
Classification (Orphanet):
(no data available)
Classification (Orphanet):
- Rare developmental defect during embryogenesis
- Rare genetic disease
- Rare odontologic disease
Classification (ICD10):
(no data available)
Classification (ICD10):
- Diseases of the digestive system -
Epidemiological data:
Class of prevalence: -
Average age onset: variable
Average age of death: -
Type of inheritance: sporadic
Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: childhood
Average age of death: -
Type of inheritance: autosomal dominant
External references:
No OMIM references
No MeSH references
External references:
1 OMIM reference -
No MeSH references
Otodental syndrome

Very frequent
- Autosomal dominant inheritance
- Tooth shape anomaly

Frequent
- Anodontia / oligodontia / hypodontia
- Broad cheeks / cherub-like / cherubin face
- Delayed dentition / eruption of teeth / lack of eruption of teeth
- Dental malocclusion
- Enamel anomaly
- Long face
- Sensorineural deafness / hearing loss
- Taurodontia
- Thickened / hypertrophic / fibromatous gingivae

Occasional
- Anophthalmos / anophthalmia / microphthalmos / microphthalmia
- Anteverted nares / nostrils
- Cataract / lens opacification
- Coloboma of iris
- Coloboma of the lens
- Heterochromia / mixed colouring of iris
- High vaulted / narrow palate
- Long philtrum
- Microcornea
- Micrognathia / retrognathia / micrognathism / retrognathism
- Pigmented naevi / naevus pigmentosus / lentigo
- Prominent / bat ears
- Retinoschisis / retinal / chorioretinal coloboma
- Supernumerary teeth / polyodontia


Pilocytic astrocytoma

(no data available)